Serum Levels of 2,3,7,8- Tetrachlorodibenzo-p-dioxin in Phenoxy Herbicide Sprayers

2,3,7,8-Tetrachlorodibenzo-p-dioxin.

Toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin.

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a persistent, bioaccumulative and toxic contaminant widely distributed in the environment. Fishes are the most sensitive vertebrates to TCDD, especially during their early developmental stages. TCDD induces various toxic effects including yolk sac edema, craniofacial malformation and neural damage in developing fish embryos. However, the effects of ...

Pathologic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in laboratory animals.

The technical chlorophenols and products produced from them, such as the herbicide 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) have been found to contain chlorodibenzo-pdioxins such as 2,3,7,8-tetrachlorodibenzo-pdioxin (TC-DD). TCDD and other chlorodibenzo-p-dioxins are among the most toxic compounds known, and have been implicated in outbreaks of chloracne among chemical workers (1). Hepatic ...

Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in aquatic organisms.

Herbicides are particularly important in modern forest management as foresters attempt to make fullest use of a constantly shrinking production base. In forestry, (2,4,5,-T) 2,4,5-trichloro-phenoxyacetic acid is used to control undesirable woody species that compete with more desirable timber-producing conifers for light, space, moisture, and nutrients. Herbicide applications can result in mark...

Exposure to dioxin and nonneoplastic mortality in the expanded IARC international cohort study of phenoxy herbicide and chlorophenol production workers and sprayers.

The authors studied noncancer mortality among phenoxyacid herbicide and chlorophenol production workers and sprayers included in an international study comprising 36 cohorts from 12 countries followed from 1939 to 1992. Exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin or higher chlorinated dioxins (TCDD/HCD) was discerned from job records and company questionnaires with validation by biologic an...